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Anabolicum Vister



Pharmaceutical Name: Quinbolone
Chemical Names: 1,4-androstadiene-3-one, 17beta-cyclopentenyl, 1-dehydrotestosterone cyclopentenyl
Chemical Formula of Base: C19H26O2
Molecular weight of Base: 286.4132
Molecular weight of Base: 352.5156
Active Life: 8-12 hours
Anabolic/Androgenic Ratio: 100/50


Quinbolone is an oral anabolic steroid utilizing the compound boldenone. Essentially it is to Equipoise what testosterone undecanoate/Andriol is to testosterone enanthate. The drug is an attempt to make an oral steroid that is not hepatoxic and therefore can be run for long periods of time without liver toxicity becoming an issue and without the inconvenience of frequent injections. The downside to such a drug is that the oral administration of the drug makes for erratic absorption rates while necessitating larger then normal dosing.

Quinbolone is boldenone with the cyclopentenyl ester attached. This ester helps facilitate fat solubility and absorption while also protecting it from metabolism before it can become active in the system of the user. Quinbolone has eliminated the need to alter the compound via 17alpha alkylation so that it can survive the first pass through the liver and remain effective by skipping this step all together. This is accomplished by having the structure of the compound able to be absorbed through the small intestine and lymphatic system (1). This is possible due to the high fat solubility that the cyclopentenyl ester provides, as well as the fact that the boldenone is combined with oil. By bypassing the liver on the first pass, this negates the need for altering the compound in anyway to ensure that it remains active and therefore no additional stress is placed on the liver.

The amount of the drug that enters a user's blood stream is dependent upon the ability of that user's lymphatic system to absorb the compound. This can vary quite dramatically from user to user. For this reason it is hard to tell exactly how much of the compound is entering the system of an individual without taking blood samples at specific times to test for this. For most users, it will be a guessing game as to how much boldenone cyclopentenyl is actually being absorbed and active. This is one of the reasons why it is not considered a complete replacement for injectable compounds.

Despite the obvious problems posed by the unreliable delivery method utilized by the compound, once the drug is fully absorbed it acts in the exact same manner as that of other boldenone compounds and brings with it all of the benefits of the compound (2). Whether or not this is worth the erratic absorption rates and large doses that are necessary is up to the user him or herself.


Use/Dosing

Due to the active life of quinbolone users should split their doses of the drug at least to two or three times per day. This should provide for enough of the compound to remain active in the system of the user for the majority of the day. More frequent dosing however would provide even more stable levels of course.

In terms of the cycle duration, quinbolone can be run for long periods of time due to the lack of negative side effects associated with the drug as well as the fact that hepatoxicity is not a concern because it is not a 17alpha alkylated drug. Users could run quinbolone for several months consecutively with little ill-effects. The only limiting factor would seemingly be the financial burden that such an undertaking would provide.

As for the specific dosing required to see results, the average male user will likely need 100 to 140 milligrams per day to achieve worthwhile results. This is keeping in mind that dramatic gains in muscle mass and/or strength will be unlikely for users to experience with this drug, even at massive daily doses. For female users doses ranging anywhere from 30 to 60 milligrams per day should be effective for most with little worry needed about negative side effects at those dosages.


Risks/Side Effects

Much like the injectable versions of the drug boldenone, quinbolone is usually well tolerated by both male and female users. Estrogenic side effects should not be a concern for the vast majority of male users as only very few will experience things such as water retention or the possibility of gynecomastia. The low rate of aromatization should not make the use of ancillary drugs necessary from quinbolone alone.

Since quinbolone is not 17alpha alkylated and is instead an oil dissolved, encapsulated oral steroid there is little to no risk of hepatoxicity related to the use of the drug (3, 4). For this reason users are not at any greater risk when using the drug for long durations of time, at least in terms of liver toxicity.

Similar to estrogenic side effects, androgenic side effects should also be close to non-existent for nearly all male users. Female users also have little to fear from this drug in terms of symptoms of virilization such as clitoral enlargement, deepening of the voice, body hair growth, etc. For the most part quinbolone is one of the mildest and least likely anabolic steroids to cause negative side effects in users.

Quinbolone is so mild and void of negative side effects in fact that it was at one time, while it was still commercially available in Italy which was the only country to actually produce the drug, prescribed to the elderly to help address some ailments related to the aging process (2). This speaks to exactly how few negative side effects and complications are associated with the administration of quinbolone.



References

1. Agostoni A, Cicardi M, Martignoni GC, Bergamaschini L, Marasini B. Danazol and stanozolol in long-term prophylactic treatment of hereditary angioedema. J Allergy Clin Immunol. 1980 Jan;65(1):75-9.

2. Llewellyn, William, Anabolics 2004, 2003-4, Molecular Nutrition, p. 71

3. Finardi G, Pedini G. [Considerations on the use of a new non 17-alpha-alkylated anabolic steroid, active orally: quinbolone. Study of liver function] Rass Fisiopatol Clin Ter. 1965 May-Jun;37(3):165-77.

4. Pyoeraelae K, Kekki M, Eisalo A. The Effect of a Non-Alkylated Anabolic Steroid, Quinbolone, On Liver Function and Anticoagulant Requirements. Ann Med Intern Fenn. 1964;53:61-8.






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